Evidence for the use of donor milk

Breastfeeding

  1. The Baby-Friendly Initiative: Protecting, promoting and supporting breastfeeding.
    Pound CM, Unger SL; Canadian Paediatric Society, Hospital Paediatrics Section, Nutrition and Gastroenterology Committee.

COVID-19 Research

  1. Holder pasteurization of donated human milk is effective in inactivating SARS-CoV-2.
    Unger S, Christie-Holmes N, Guvenc F, Budylowski P, Mubareka S, Gray-Owen SD, O’Connor DL.

Donor milk and Religious Beliefs

  1. Implications for observant Jewish families in the provision of mother’s own and donor milk for their very low birth weight infant.
    Kassierer MY, O’Connor DL, Rutherford E, Rolnitzky A, Unger S.
  2. The concept of milk kinship in Islam: issues raised when offering preterm infants of Muslim families donor human milk.
    El-Khuffash A, Unger S.

Maternal Studies

  1. Mothers of Preterm Infants Have Individualized Breast Milk Microbiota that Changes Temporally Based on Maternal Characteristics.
    Asbury MR, Butcher J, Copeland JK, Unger S, Bando N, Comelli EM, Forte V, Kiss A, LeMay-Nedjelski L, Sherman PM, Stintzi A, Tomlinson C, Wang PW, O’Connor DL.
  2. Examining the relationship between maternal body size, gestational glucose tolerance status, mode of delivery and ethnicity on human milk microbiota at three months post-partum.
    LeMay-Nedjelski L, Butcher J, Ley SH, Asbury MR, Hanley AJ, Kiss A, Unger S, Copeland JK, Wang PW, Zinman B, Stintzi A, O’Connor DL.
  3. Maternal Diet and Infant Feeding Practices Are Associated with Variation in the Human Milk Microbiota at 3 Months Postpartum in a Cohort of Women with High Rates of Gestational Glucose Intolerance.
    LeMay-Nedjelski L, Asbury MR, Butcher J, Ley SH, Hanley AJ, Kiss A, Unger S, Copeland JK, Wang PW, Stintzi A, O’Connor DL.
  4. Oligosaccharides and Microbiota in Human Milk Are Interrelated at 3 Months Postpartum in a Cohort of Women with a High Prevalence of Gestational Impaired Glucose Tolerance.
    LeMay-Nedjelski L, Yonemitsu C, Asbury MR, Butcher J, Ley SH, Hanley AJ, Kiss A, Unger S, Copeland JK, Wang PW, Stintzi A, Bode L, O’Connor DL.

Neurodevelopment

  1. Effect of Supplemental Donor Human Milk Compared With Preterm Formula on Neurodevelopment of Very Low-Birth-Weight Infants at 18 Months: A Randomized Clinical Trial.
    O’Connor DL, Gibbins S, Kiss A, Bando N, Brennan-Donnan J, Ng E, Campbell DM, Vaz S, Fusch C, Asztalos E, Church P, Kelly E, Ly L, Daneman A, Unger S; GTA DoMINO Feeding Group.
  2. Nutrient Enrichment of Human Milk with Human and Bovine Milk-Based Fortifiers for Infants Born <1250 g: 18-Month Neurodevelopment Follow-Up of a Randomized Clinical Trial.
    Hopperton KE, O’Connor DL, Bando N, Conway AM, Ng DVY, Kiss A, Jackson J, Ly L; OptiMoM Feeding Group, Unger SL.
  3. DoMINO: Donor milk for improved neurodevelopmental outcomes.
    Unger S, Gibbins S, Zupancic J, O’Connor DL.
  4. Socio-emotional functioning and dietary intake among children born with a very low birth weight
    Walton K, McGee M, Sato J, Law N, Hopperton K, Bando N, Kiss A, Unger S, O’Connor D. 
  5. Eating behaviours, caregiver feeding interactions and dietary patters of children born preterm: A systematic review & meta-analysis
    Walton K, Daniel AI, Mahood Q, Vaz S, Law N, Unger S, O’Connor DL.

Nutrition and Health

  1. Early nutrition and white matter microstructure in children born very low birth weight.
    Sato J, Vandewouw MM, Bando N, Ng DVY, Branson HM, O’Connor DL, Unger SL, Taylor MJ.
  2. Associations between Diet Quality and Body Composition in Young Children Born with Very Low Body Weight.
    McGee M, Unger S, Hamilton J, Birken CS, Pausova Z, Kiss A, Bando N, O’Connor DL.
  3. Lean mass accretion in children born very low birth weight is significantly associated with estimated changes from sedentary time to light physical activity.
    McGee M, Unger S, Hamilton J, Birken CS, Pausova Z, Vanderloo LM, Bando N, O’Connor DL.
  4. Supplementation of Mother’s Own Milk with Donor Milk in Infants with Gastroschisis or Intestinal Atresia: A Retrospective Study.
    Hoban R, Khatri S, Patel A, Unger SL.
  5. Optimizing the growth of very-low-birth-weight infants requires targeting both nutritional and nonnutritional modifiable factors specific to stage of hospitalization.
    Asbury MR, Unger S, Kiss A, Ng DVY, Luk Y, Bando N, Bishara R, Tomlinson C, O’Connor DL; GTA-DoMINO Feeding Group.
  6. Energy and Fat Intake for Preterm Infants Fed Donor Milk Is Significantly Impacted by Enteral Feeding Method.
    Castro M, Asbury M, Shama S, Stone D, Yoon EW, O’Connor DL, Unger S.
  7. Postdischarge Feeding of Very-low-birth-weight Infants: Adherence to Nutrition Guidelines.
    Francis J, Unger S, Bando N, Vance A, Gibbins S, Kiss A, Church P, Sellen D, O’Connor DL; GTA-DoMINO Feeding Group.
  8. Nutrient enrichment of human milk with human and bovine milk-based fortifiers for infants born weighing <1250 g: a randomized clinical trial.
    O’Connor DL, Kiss A, Tomlinson C, Bando N, Bayliss A, Campbell DM, Daneman A, Francis J, Kotsopoulos K, Shah PS, Vaz S, Williams B, Unger S; OptiMoM Feeding Group.
  9. Independent of Birth Mode or Gestational Age, Very-Low-Birth-Weight Infants Fed Their Mothers’ Milk Rapidly Develop Personalized Microbiotas Low in Bifidobacterium.
    Butcher J, Unger S, Li J, Bando N, Romain G, Francis J, Mottawea W, Mack D, Stintzi A, O’Connor DL.
  10. Neonatal Morbidity Count Is Associated With a Reduced Likelihood of Achieving Recommendations for Protein, Lipid, and Energy in Very Low Birth Weight Infants: A Prospective Cohort Study.
    Ng DVY, Unger S, Asbury M, Kiss A, Bishara R, Bando N, Tomlinson C, Gibbins S, O’Connor DL; GTA-DoMINO Feeding Group.
  11. Methods and Strategies to Examine the Human Breastmilk Microbiome.
    LeMay-Nedjelski L, Copeland J, Wang PW, Butcher J, Unger S, Stintzi A, O’Connor DL.
  12. How Close Are We to Achieving Energy and Nutrient Goals for Very Low Birth Weight Infants in the First Week?
    Ng DV, Brennan-Donnan J, Unger S, Bando N, Gibbins S, Nash A, Kiss A, O’Connor DL.
  13. Human Milk for Ill and Medically Compromised Infants: Strategies and Ongoing Innovation.
    DiLauro S, Unger S, Stone D, O’Connor DL.
  14. Introduction of Bovine-Based Nutrient Fortifier and Gastrointestinal Inflammation in Very Low Birth Weight Infants as Measured by Fecal Calprotectin.
    Panczuk JK, Unger S, Francis J, Bando N, Kiss A, O’Connor DL.
  15. Gut microbiota of the very-low-birth-weight infant.
    Unger S, Stintzi A, Shah P, Mack D, O’Connor DL.
  16. Post-discharge nutrition of the breastfed preterm infant.
    O’Connor DL, Unger S.
  17. Human donor milk for the vulnerable infant: a Canadian perspective.
    Panczuk J, Unger S, O’Connor D, Lee SK.
  18. State of the evidence from clinical trials on human milk fortification for preterm infants
    Beggs MR, Bando N, Unger S, O’Connor DL
  19. Docosaheaenoic acid and arachidonic acid levels are correlated in human milk: Implications for new European infant formula regulations
    Hopperton KE, Pitino MA, Walton K, Kiss A, Unger SL, O’Connor DL, Bazinet RP

Pasteurization

  1. Impact of holder, high temperature short time and high hydrostatic pressure pasteurization methods on protein structure and aggregation in a human milk protein concentrate.
    Sergius-Ronot M, Pitino MA, Suwal S, Shama S, Unger S, O’Connor DL, Pouliot Y, Doyen A.
  2. The ultrafiltration molecular weight cut-off has a limited effect on the concentration and protein profile during preparation of human milk protein concentrates.
    Sergius-Ronot M, Suwal S, Shama S, Chamberland J, Unger S, O’Connor DL, Pouliot Y, Doyen A.
  3. The impact of thermal pasteurization on viral load and detectable live viruses in human milk and other matrices: a rapid review.
    Pitino MA, O’Connor DL, McGeer AJ, Unger S.
  4. Pasteurized and unpasteurized donor human milk.
    Pound C, Unger S, Blair B.
  5. Les dons de lait humain pasteurisé et non pasteurisé.
    Pound C, Unger S, Blair B.
  6. La pasteurisation à l’aide de la méthode de Holder appliquée au lait maternel provenant de donneuses permet d’inactiver le SRAS-CoV-2.
    Unger S, Christie-Holmes N, Guvenc F, Budylowski P, Mubareka S, Gray-Owen SD, O’Connor DL.
  7. Oxylipin concentration, but not fatty acid composition, is altered in human donor milk pasteurised using both thermal and non-thermal techniques.
    Pitino MA, Alashmali SM, Hopperton KE, Unger S, Pouliot Y, Doyen A, O’Connor DL, Bazinet RP.
  8. Human milk pasteurization: benefits and risks.
    O’Connor DL, Ewaschuk JB, Unger S.
  9. Effect of pasteurization on immune components of milk: implications for feeding preterm infants.
    Ewaschuk JB, Unger S, Harvey S, O’Connor DL, Field CJ.
  10. High Hydrostatic Pressure Processing Better Preserves the Nutrient and Bioactive Compound Composition of Human Donor Milk.
    Pitino MA, Unger S, Doyen A, Pouliot Y, Aufreiter S, Stone D, Kiss A, O’Connor DL.

The Use of Donor Milk

  1. Cost-Effectiveness of Supplemental Donor Milk Versus Formula for Very Low Birth Weight Infants.
    Trang S, Zupancic JAF, Unger S, Kiss A, Bando N, Wong S, Gibbins S, O’Connor DL; GTA DoMINO Feeding Group.
  2. Impact of Neonatal Intensive Care Unit Admission on Bacterial Colonization of Donated Human Milk.
    Elmekkawi A, O’Connor DL, Stone D, Yoon EW, Larocque M, McGeer A, Unger S.
  3. Is Frozen Human Milk That Is Refused by Mother’s Own Infant Suitable for Human Milk Bank Donation?
    Pitino MA, Stone D, O’Connor DL, Unger S.
  4. Adiposity and Fat-Free Mass of Children Born with Very Low Birth Weight Do Not Differ in Children Fed Supplemental Donor Milk Compared with Those Fed Preterm Formula.
    McGee M, Unger S, Hamilton J, Birken CS, Pausova Z, Kiss A, Bando N, O’Connor DL.
  5. Term Infants Fed Exclusively With Donor Milk May Require Vitamin C Supplementation.
    Castro M, Pitino MA, Bando N, Aufreiter S, Stone D, O’Connor DL, Unger S.
  6. Determinants of fatty acid content and composition of human milk fed to infants born weighing <1250 g.
    Hopperton KE, Pitino MA, Chouinard-Watkins R, Shama S, Sammut N, Bando N, Williams BA, Walton K, Kiss A, Unger SL, Bazinet RP, O’Connor DL.
  7. Predicting Protein and Fat Content in Human Donor Milk Using Machine Learning.
    Wong RK, Pitino MA, Mahmood R, Zhu IY, Stone D, O’Connor DL, Unger S, Chan TCY.
  8. A Human Milk-Based Protein Concentrate Developed for Preterm Infants Retains Bioactive Proteins and Supports Growth of Weanling Rats.
    Shama S, Unger S, Pouliot Y, Doyen A, Suwal S, Pencharz P, Pitino MA, Sergius M, Aufreiter S, Stone D, O’Connor DL.
  9. Developing global guidance on human milk banking.
    Tyebally Fang M, Chatzixiros E, Grummer-Strawn L, Engmann C, Israel-Ballard K, Mansen K, O’Connor DL, Unger S, Herson M, Weaver G, Biller-Andorno N.